Frozen-solution conformational analysis by REDOR spectroscopy.
نویسندگان
چکیده
Frozen-solution conformational analysis (FrSCA) can be performed on organic compounds using REDOR spectroscopy. REDOR measurements on frozen aqueous solutions of 13C-methyl beta-15N-aminoglucoside indicate a bimodal distribution of conformations in a 68:32 ratio, with 13C-15N distances of 4.31 and 3.55 A, respectively. The high resolution and straightforward sample preparation make FrSCA an attractive alternative to solution-based NMR methods of conformational analysis.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 125 49 شماره
صفحات -
تاریخ انتشار 2003